![]() There are strong associations between VV and DVT in a general practice population with documented VV. An increased risk of DVT was associated with previous DVT (adjusted odds ratio (OR): 9.07, 95 % confidence interval (CI): 7.78 - 10.91), VV (OR 7.33 ), hospitalization during the last 6 months (OR 1.69 ), malignancy (OR 1.55 ), and age (OR 1.02 ). There were 132 out of 2,357 (5.6 %) DVT episodes among patients with VV compared to 728 out of 80,588 (0.9 %) in the patient cohort without VV (p < 0.0001). A potential cluster effect (patients within practices) was regarded in the regression model. The SAS procedure "PROC GENMOD" (SAS version 9.2, 64-bit) was parameterised accordingly. Multivariate binary logistic regression was performed in order to assess potential risk factors for DVT. ![]() The covariates age, gender, surgery, hospitalization, congestive heart failure, malignancy, pregnancy, hormonal therapy, and respiratory infection were extracted for each patient. The exposure of VV and DVT was based solely on ICD coding without regarding the accuracy of the diagnosis. The aim of this study in primary care was to determine the impact of varicosity as a potential risk factor for developing DVT.ĭuring the observation period between 0 and 0, all cases with VV (ICD code I83.9) and DVT (ICD codes I80.1 - I80.9) were identified out of the CONTENT primary care register (Heidelberg, Germany). ![]() The role of varicose veins (VV) as a risk factor for development of deep venous thrombosis (DVT) is still controversial.
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